Top 6 Antibody-Drug Conjugate (ADC) startups

Oct 11, 2024 | By Jason Kwon

These startups develop ADC cancer therapies that combine monoclonal antibodies with cytotoxic drugs, delivering the drug directly to cancer cells thus minimizing damage to healthy tissues.
1
Country: Denmark | Funding: $114.6M
ADCendo is dedicated to developing antibody-drug conjugates (ADCs) for treatment of cancer. We are taking the ADC approach to new levels through a focus on cancer-associated targets that are professional internalizers and allow for superior selectivity via highly preferential cancer expression.
2
Country: UK | Funding: $188M
Pheon Therapeutics is an Antibody-Drug Conjugate (ADC) specialist that creates ADCs for a variety of difficult-to-treat cancers.
3
Country: Switzerland | Funding: $751.6M
ADC Therapeutics is focused on the development of proprietary Antibody Drug Conjugates (ADCs) for the treatment of both solid and hematological cancers. ADC Therapeutics employs monoclonal antibodies specific to particular tumor antigens conjugated to a novel class of highly potent pyrrolobenzodiazepine (PBD) -based warheads to selectively kill cancer cells.
4
Country: USA | Funding: $247M
ProfoundBio is a developer of targeted therapeutics intended for patients with cancer.
5
Country: Germany | Funding: €200M
Tubulis Technologies generates uniquely matched protein-drug conjugates ADCs that deliver drugs to tumors but still cause adverse events by shedding their payloads en route to the cancer.
6
Country: Switzerland | Funding: $65.7M
NBE-Therapeutics develops next-generation ADCs improving treatment options for cancer patients. The company is financially backed by the Boehringer Ingelheim Venture Fund and additional private investors.
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com