Top 100 medical and healthcare startups in USA

Sep 18, 2025 | By Jason Kwon

1
Funding: $435M
Lila Sciences creates a scientific superintelligence platform and autonomous labs for life sciences, chemistry, and materials science.
2
Funding: $172M
Wugen is developing off-the-shelf cellular therapies targeting solid tumors and hematologic malignancies
3
Funding: $75.5M
Assort Health provides voice AI agents designed for healthcare call centers, enabling automation of appointment management tasks.
4
Funding: $64.3M
Arnatar Therapeutics is a biopharmaceutical company that specializes in the development of novel nucleic acid medications.
5
Funding: $1.1B
Treeline Biosciences is a biotech company building transformative precision medicines for patients with cancer and other serious conditions.
6
Funding: $141M
Antiva Biosciences is a biopharmaceutical company developing therapeutics for the treatment of diseases caused by HPV infection.
7
Funding: $194.4M
ReShape Lifesciences is a developer of minimally invasive medical devices to treat obesity and metabolic diseases.
8
Funding: $112.3M
Solera allows health plans and employers to securely and efficiently leverage a network of community and digital health solutions.
9
Funding: $106.6M
An Immersive Medical Learning Platform. From anatomical representation to procedural planning, zSpace brings a new dimension to medical learning and visualization.
10
Funding: $97.8M
ChromaCode is a molecular diagnostics company focusing on bioinformatics.
11
Funding: $48.8M
PictorLabs is developing a virtual staining platform for histopathology, or the microscopic exam of tissue
12
Funding: $28M
CellFE is a company developing a microfluidics based device to deliver gene-editing molecules.
13
Funding: $10.2M
Carallel offers a caregiver support solution that combines digital tools with personal guidance from senior care experts.
14
Funding: $898.9M
Janux Therapeutics develops immunotherapies that generates immune responses to prevent tumors and not affecting a patient’s healthy tissue.
15
Funding: $654.1M
Innovaccer is a leading healthcare data activation company committed to making powerful & enduring difference in the way care is delivered.
16
Funding: $553.5M
Invivyd develops antibodies to transcend the limitations of the human immune system and fight against viral infections.
17
Funding: $529.9M
Enveda Biosciences is a biotechnology company engineering new drugs from plants.
18
Funding: $505M
Our purpose is to reduce the physical, emotional and economic burdens of obesity as a driver of diseases, creating value for the people we serve and the investors we work for.
19
Funding: $496M
Invivyd develops antibodies to transcend the limitations of the human immune system and fight against viral infections.
20
Funding: $337M
Exo is pioneering a high-performance handheld ultrasound platform and AI for imaging and therapeutic applications.
Editor: Jason Kwon
Jason Kwon is a senior editor for MedicalStartups. He has previously covered the pharmaceutical and medical research industries for FDAnews and worked as a head of marketing for medical startup Sonic Therapeutics. Before that, he co-founded a startup consulting business for emerging entrepreneurial hubs in Asia. Jason graduated from St. Bonaventure University’s journalism school. In his free time, Jason enjoys yoga, watching movie trailers, traveling to places where he can't get cell service. You can contact Jason at jaskwon(at)medicalstartups(dot)com